You can also right-click a message and select “Ignore” from the pop-up menu. Alternatively, select the message and press the “Ctrl” + “Delete” or “Ctrl” + “Del” keys on your keyboard to ignore the conversation. Then click the “Ignore” button in the “Delete” button group of the “Home” tab in the Ribbon. To ignore a conversation in Outlook, find and click on the conversation in the Inbox pane of the folder that contains the message. It only blocks or ignores future emails in the same conversation stream.
While this feature ignores any new emails in the conversation stream, it doesn’t block or ignore emails from any senders or other recipients. This is a helpful feature if you are no longer a part of an email conversation.
You can ignore a conversation in Outlook that you no longer want to see in your Inbox. Ignore a Conversation in Outlook: Overview